Guarantees a Planetarium if an item room has been skipped, otherwise +15% chance for Planetariums to spawn while held. Items picked up are not shared between the two characters, UNLOCK: Unlock this item by defeating The Beast as Tainted Jacob, When activated, Isaac's tears are replaced by a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up for 5 seconds, The sword deals x3 damage if used at close range, or x1.5 damage if charged up and thrown, Clearing rooms doesn't charge this item - charge is added equal to damage taken by enemies. Deals 45 damage to enemies it lands on. Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. The true values of Isaac's stats are still calculated normally, but the best values will override them. ?, Satan and The Lamb as Tainted Eve, A small clot friend will hug Isaac, following his exact movements (similar to how Jacob & Esau work) and shooting tears when he does, The clot can be moved around by collision with an object/wall, allowing you to re-position it, The clot's damage is roughly 1/3 of your tear damage, If it takes a few hits it will die, and respawn in the next room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eve, Spawns a random chest after completing a regular Challenge Room, Spawns a pedestal item after completing a boss Challenge Room, UNLOCK: Unlock this trinket by defeating Isaac, ?? Without the long-range version, his mini-brimstone won't have enough length to use any homing items. * item room, treasure room, item room pool, round, circle, white, REPENTANCE - Homing tears now target enemies much more reliably, * item room, treasure room, item room pool, grey, gray, bent, x1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier), Cricket's Head used to be known as Max's Head in the original game and was renamed for Rebirth, * crickets head, cricket head, item room, treasure room, item room pool, golden chest pool, gold chest pool, cat, dead, brown, pink, * item room, treasure room, item room pool, broken, mirror, cracked, grey, gray, silver, Gives you a very high tear rate in exchange for a big range down, * item room, treasure room, item room pool, mm sweet lemonade, urine, yellow, tear, drop, x1.5 times Damage Multiplier if you also have Book of Belial (Does not stack with Magic Mushroom or Cricket's Head multipliers), * item room, treasure room, item room pool, crown, thorns, brown, hat, A familiar which follows Isaac and shoots normal tears which do 3.5 damage, Counts as 1 of 3 familiar items needed towards the Conjoined transformation, REPENTANCE - Brother Bobby now has an increased rate of fire, * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, purple, blue, dead, baby, A lot of fly enemies are no longer aggressive towards Isaac, Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly, Boom Fly, Red Boom Fly, Drowned Boom Fly move slower, but still deal contact damage, Moter, Level 2 Fly, Full Fly, Pooter, and Super Pooter move slower and deal no contact damage, Can only be obtained from the shell game in the arcade, Counts as 1 of 3 fly items needed towards the Beelzebub transformation. - The Binding Of Isaac: Repentance Ep. The spear occasionally inflicts fear on enemies it damages. These only appear if not all runes have been unlocked yet. brown, brass, copper, dads key, dad key, * boss room pool, boss room item, item room, treasure room, item room pool, lumpy, red, balls, Using the portable slot takes a coin and has a chance to give a pickup - similar to how the normal slot machines work, REPENTANCE - The delay between uses was removed, allowing you to spam-use it, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, The effect is weaker than normal runes. You can play The Binding of Isaac on your Android smartphone with this app in the same way that you would on a computer. box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. The size resets when leaving the floor, UNLOCK: Unlock this item by defeating The Beast as Tainted Lazarus, A fetus familiar follows Isaac, and upon entering the Boss room on each floor, it will transform into a copy of the boss, This makes bosses a lot harder, however you now get 2 boss item drops, UNLOCK: Unlock this item by defeating Hush as Jacob & Esau, You gain two familiar demons, that stay by Isaac's side and fire shots in the same direction as you, The familiars deal roughly 40% of Isaac's damage, scaling with damage upgrades you get, They sit near and rotate around Isaac depending on which way you're firing tears. ), Prevents your stats from being reduced any more for the rest of the run, e.g. golden, yellow, glow, A familiar that follows Isaac and blocks any shots that hit it, If a projectile is blocked by Dry Baby, he has a 10% chance to activate the Necronomicon effect, dealing 40 damage to the entire room, The chance to activate the effect is not changed by your Luck stat, * item room, treasure room, item room pool, dry baby is best baby, northernlion, fat skeleton, Counts as 1 of 3 spider items needed towards the Spider Baby transformation. 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Hook Worm, Wiggle Worm etc. 5c pickups become 3c. ?s only friend, blue bozzy, An iron ball and chain attached to Isaac, similar to Guppy's Hairball that you can fling around to deal 5 damage per tick, The ball will block enemy shots and can also destroy environmental objects such as rocks, mushrooms and skulls, Does not decrease your movement speed stat at all however the ball has to be dragged around causing Isaac to slow down slightly when the chain is fully extended, UNLOCK: Unlock this item by beating Boss Rush with Samson, * secret room pool, item room, treasure room, item room pool, grey, gray, shackle, A familiar that will follow Isaac and copy the effect of one of your other familiars, If you don't have any other familiars, he will just shoot normal tears, REPENTANCE - Removed the double damage multiplier on Mongo Baby's attacks, * item room, treasure room, item room pool, pink, blue, grey, gray, An active item that fires 8 of Isaac's tears in a circle around him, Tears spawned from this item keep most effect that Isaac currently has applied to his tears, and deal an additional +5 flat damage, UNLOCK: Unlock this item by beating the Isaac boss with Isaac, * item room, treasure room, item room pool, glass, blue, water, isaacs tears, Upon use, teleports you to one of the following rooms at random: Item room, Secret room, Super secret room, the I AM ERROR room or the Black Market (very low chance), There are no I AM ERROR rooms on the final floors, preventing looping with this item, UNLOCK: Unlock this item by beating Boss Rush with Eden, * item room, treasure room, item room pool, pink, purple, red, broken, When used will cut your head from your body. Item Descriptions [1-10] CROWBAR "Create Your Own Entrance" Type: Active (3 Room Charge) Item Pool: Shop This effect is stackable, *, the lost item pool, pink, red, guts, intestine, tube, Gives Isaac a higher chance to find hearts from drops after clearing a room and from chests, * , the lost item pool, red, purple, childs heart, child heart, UNLOCK: Unlock this item by beating the Dark Room with Judas, Gives Isaac a higher chance to find keys and chests, Grants a secondary chance of any non-specific heart drop turning into a soul heart, * , the lost item pool, white, grey, gray, circle, round, moms pearl, The fire rate increase is applied in such a way that the higher your tear stat is, the more effective Cancer is, Breaks the normal fire rate cap, allowing you to fire faster than the normal maximum, You have a chance when taking damage to gain +1.8 Damage Up for the rest of the room, Gives Isaac a higher chance to find bombs, Picking up the Match Stick is the only way to remove the Tick trinket, UNLOCK: Unlock this item by blowing up 20 shop keepers (this includes the ones in the secret room), When you take damage while on 1/2 a heart, you are teleported back to the previous room. This can make it confusing while navigating the room, Dataminer will randomly increase or decrease one of your stats by a small amount when used, Gives you the Fruit Cake effect for the room when used, which will give a random tear effect with every tear fired, All visual and tear effects reset after leaving the room, * data miner, red, pickaxe, minecraft, pixel, When used, this item will randomly change you into another character and remove the last item you picked up, All stat changes of the new character are applied (e.g. blue, white, triangle, Isaac's tears become large, brown and will penetrate all objects and enemies (piercing + spectral), Despite the increase in tear size, Dead Onion does NOT increase your damage stat. This is to prevent a syngery like Dr. Fetus or a Golden Bomb giving you infinite resources, Isaac's shadow will follow closely behind him and when it comes into contact with enemies, will spawn friendly dark charger mobs, The chargers deal contact damage to enemies, and will be killed if it is hurt too much, Chargers disappear upon entering a new room, UNLOCK: Unlock this item by beating Greed Mode with Judas, Every time you kill an enemy a fly will be added to the Jar, allowing you to stack up to 20, Using the Jar of Flies will release all the flies that are currently in the jar as friendly flies that will damage enemies, A Loki familiar that follows Isaac and shoots tears 4 tears in a cross pattern, dealing a flat 3.5 damage each, Gives Isaac a familiar glass of milk that follows him and spills on the floor upon taking damage, After being spilt, the milk gives you a -2 Tear Delay (Tears up) for the rest of the room, When used, the D7 will restart the current room and bring back all enemies once again, enabling you to farm rewards that spawn at the end after beating the room, Can be used to generate infinite consumable combinations, gaining as many coins/keys/bombs as you need, This item has no effect in Greed Mode, Challenge Rooms and rooms that had no enemies in originally, If used in a Boss Room or Angel/Devil Room, you get teleported to another random room, which is reset instead of the boss/angel/devil room you were in, Enemies respawned by the D7 don't drop loot if they were champions and also don't grant score in daily runs, * dice, pip, die, turban, white, grey, gray, Makes Isaac very small like a baby, reducing his hitbox size, When used, Mom's Box will drop a random trinket on the ground, While held, doubles the effect of trinkets which make sense to be doubled (e.g. ), Doesn't show the location of Secret or Super Secret rooms, Room icons will not show if a Curse of the Lost is in effect on the current floor, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Heals one red heart container when picked up, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow. sack, pouch, blue, purple, Tears gain a damage up and increase in size based on the distance they travel, The length of a normal room roughly gives +6 damage, but this can be higher with double rooms or Tiny Planet, This item synergises with beam items such as Brimstone and Tech, allowing them to do more damage the further away the enemy is, When used, removes one heart container and gives you 3 soul hearts, Item Pool: Devil Room, Curse Room, Red Chest, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, purple, pink, circle, guppys collar, All of Isaac's tears now have a shield, allowing them to block an enemy projectile, If a tear blocks something, both Isaac's and the enemies tears are destroyed, * secret room pool, item room, treasure room, item room pool, white, lump, oval, When Isaac takes damage, he will start to leave a trail of blood creep behind him as he walks for the current room. Enemies touching the head don't hurt Isaac, UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten, Item Pool: Boss Room, Crane Game, Golden Chest, Drops 1 random rune or soul stone when picked up, Item Pool: Shop, Golden Chest, Mom's Chest, Old Chest, Each time you get hit, you drop a coin or two, REPENTANCE - No longer guaranteed to drop coins as The Keeper, UNLOCK: Unlock this item by beating Challenge #15 (Slow Roll), * , the lost item pool, cent, gold, water, wet, blue, While held, Isaac has a significantly higher chance to find drops when breaking poops, Lowers your spacebar item charge rate by 1, Cannot lower the charge of your spacebar item below 1 room, For example, you will now be able to use a 3 room charge item after 2 rooms instead, Does the teleport effect every time you use your current spacebar item, Can be used infinitely every room if you have Guppy's Paw and no red heart containers (Can be exploited to get to the boss room without clearing any other rooms), Higher chance for champion enemies while held, Has a partial Magneto effect and will attract coins, pulling them into Isaac from a distance, Does not attract other pickups like the full Magneto item does, Increases your chances to find an Angel Room instead of a Devil Room, Normally there is a 50%/50% chance of a Angel or Devil room with if a door spawns after the boss. devil room pool, devil deal, paper, pink, brown, isaac, Gives a 50% chance to not take damage from projectiles, * golden chest pool, gold chest pool, secret room pool, item room, treasure room, item room pool, Gives Isaac an orbital fly, that will rapidly charge around and deflect any incoming tears that would hit Isaac. princezzxdiana, pink, purple, hat, Once per room when you are damaged down to your final half a heart, you gain 1 soul heart, Re-entering a room allows this effect to be triggered again. It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation. UNLOCK: Unlock this item by beating the Isaac boss with Azazel, * the satanic bible library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, the lost item pool, pentagram, star, grey, gray, red, When used, fires a 4 way brimstone laser in all cardinal directions, dealing a lot of damage to any enemies, Laser damage does not scale with your damage stat - its a fixed 10 damage per tick for 20 ticks (200 total per use), Has a chance to drop after you beat Krampus, If you get close enough to an enemy that has a large hitbox, you can hit it with 2 of the laser beams, allowing you to deal more damage, UNLOCK: Unlock this item by beating Krampus (Krampus is unlocked by taking 20 devil deal items), *, horns, grey, gray, white, red, dead, tongue, krampus head, When used, farts on nearby enemies and knocks them backwards away from Isaac, Allows you to reflect projectiles away from Isaac, REPENTANCE - Butter Bean now knocks back enemies and projectiles with significantly more force. If used with Brimstone you have a 100% chance to fire a laser out the back of your head, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, This effect stacks with multiple shades, scaling the contact damage each time, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Judas, Isaac gains a cloud familiar that follows him and leaves a trail of tears on the floor which damages enemies for 2 damage per tick, Enemies touching the cloud have a chance to activate the Crack the Sky effect, which spawns a light beam that deals damage equal to your tear damage + 20, Gives Isaac a small Hush familiar that bounces diagonally around the room dealing 2 contact damage per tick, While you're firing tears Hushy will stop moving, which allows you to keep it in one place, Hushy will block enemy tears and projectiles, UNLOCK: Unlock this item by beating Hush with Apollyon, Gives Isaac a small Monstro familar, who's tears can be charged and released in a shotgun style effect, much like Monstro's main attack, Lil Monstro's tears each deal base damage (3.5) and don't scale with damage upgrades, *, head, cleft, lip, palate, hairlip, tooth, A baby familiar that follows you and causes other familiars to follow it. It's a 20% chance on first miss, 33% for a second miss and 50% for anything beyond that, Piercing shots work with this item and multiple hits with a single tear will each give a damage bonus, *, bullseye, target, grey, gray, black, red, circle, Isaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a light beam on the same enemy, dealing damage, The beams from this item deal damage equal to 400% of your tear damage (4x damage multiplier for the beams only), The chance to fire a Holy tear is affected by your luck stat, maxing out at a 50% chance, Item Pool: Item Room, Greed Mode Item Room, Angel Room, A familiar host that sits on Isaac's head and has a 20% chance to block enemy shots, When a shot is blocked, Host Hat will fire 3 bullets back at the enemy, Causes you to become immune to explosions, but doesn't protect against stomps or shockwaves, Causes your shops to instantly restock their items when you buy them, New items generated by Restock are from the shop item pool, The cost increases exponentially every time you purchase an item. Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row), I'm Drowsy - Slows all enemies for the rest of the current room, I'm excited!!! This allows you to choose between the item that originally spawned and a HP upgrade every time, This effect applies to most items, including those in the shop and devil room. REPENTANCE - Dark Prince's Crown now grants more of an increase in rate of fire, and the bonus now breaks the soft tears cap. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost', If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway, UNLOCK: Unlock this item by beating the Chest with Eden, 80% of heart drops are replaced with keys, Hearts turn into black hearts where possible. Isaac doesn't take damage from this effect, UNLOCK: Unlock this item by defeating Delirium as Tainted Lost, Spawns a familiar that's attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting, When activated you first need to throw the familiar, which deals x3 your tear damage to any enemies it touches, Gello's tears deal x0.75 your tear damage (x1.0 if Lilith), Can be used multiple times per room to spawn more familiars, however they only last for the current room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith, When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again, Throwing Isaac's head deals 24 damage to anything it hits while being thrown, Your hitbox remains with the body. These stack with multiple secret rooms - The first one gives +1.00 Tears Up, then all future ones give +0.5. How To See What Items Do In Binding Of Isaac - YouTube Can be used with Placebo to generate infinite batteries, Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). Based on the Steam Workshop mod created by electoon and Erfly, *, dark side of the moon, rainbow, red, yellow, green, white, triangle, pink floyd, thought, Replaces Isaac's tears with eyeballs that can bounce off of each other, Issac's tears are no longer limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle, Added as part of the Afterbirth+ Booster Pack #3. Holding the fire button charges a spin attack (Damage * 8 + 10). Pressing 3 yellow buttons on the floor causes the minecart to be rideable. REPENTANCE - +0.2 Speed Up (Used to be -0.1 Speed before Repentance). Takes more shots before breaking, Bomb poop - Throws a butt bomb that explodes after 2 seconds, UNLOCK: Unlock this item by defeating Delirium as Tainted Blue Baby, Allows you to quickly double tap a shoot button to sneeze on nearby enemies, dealing x1.5 your tear damage and pushing them back slightly, If an enemy is pushed into a wall or object it takes 10 damage, UNLOCK: Unlock this item by defeating Delirium as Tainted Azazel, Bombs become spectral and can now pass through objects, Bombs spawn a friendly white soul, which will hunt down other enemies, dealing contact damage which scales with your tear damage, After 10 seconds the white soul explodes dealing 7 damage to nearby enemies. This page documents some of the more noteworthy item synergies available. Mr. Peppino in The Binding of Isaac : r/thebindingofisaac ?, Satan and The Lamb as Tainted Judas, Changes Devil Room layouts. The Mega Mush is a new mushroom-type item in The Binding Of Isaac: Repentance and, like the other mushrooms, significantly affects the player's stats. They do not block enemy shots, UNLOCK: Unlock this item by defeating The Beast as Tainted Lilith, Isaac builds rage each time you clear a new room. ?, Satan and The Lamb as Tainted Apollyon, Gives you a red attack fly, that will charge at enemies in the same direction you are shooting, Deals damage equal to your current tear damage, Stops charging once it hits an enemy and returns to Isaac's side, UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon, Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. * devil pool, devil room pool, devil deal, the lost item pool, cross, upside down, red, black. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. 3 keys = 25% chance. The stationary head is now affected by Isaac's stats and attack modifiers, and the body will spew a controllable fountain of blood shots. If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful! at base damage of 3.5, that's 45 damage), Self-inflicted damage such as Blood Donation machines don't trigger this effect, Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide), Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar. 3. r/thebindingofisaac. Steam Community :: Guide :: [UPDATED] How to Create a Custom Character This room isn't part of the actual floor, and leaving it returns you to where you teleported from, The boss isn't necessarily from the current floor - e.g. How to use Binding of Isaac item editor - YouTube You can release the enemy early by using it again, Tainted Jacob starts with this item. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, grey, gray, deaths touch, death touch, Increases your chances to find an Angel Room instead of a Devil Room. ?, Satan and The Lamb as Tainted Bethany, Taking damage gives you a chance to spawn a flame orbital, similar to the ones created by Book of Virtues, Entering an Angel Room gives you +5 flame orbitals. Shows you to see the contents of chests, sacks, shopkeepers and items that will drop from fires before you destroy them, Doesn't work on tinted rocks and other obstacles (e.g. Enemies include Candler, Lil' Haunt, Polty, Red Ghost, Wizoob and The Forsaken, The Haunt, The Heretic and The Rainmaker bosses. They modify Isaac's Attributes, grant or modify Tear Effects, and much more. REPENTANCE - White poop from Hallowed Ground is now more durable, similar to golden poop. spray, brown, white, yellow, moms purfume, Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack, Partial charging does nothing - must be fully charged to use, * item room, treasure room, item room pool, pink, body part, monstros lung, On pickup Abaddon converts all your heart containers to black hearts, then gives you +2 more black hearts, Tears now have a chance to induce the fear effect, causing enemies to run away from Isaac for a short period, REPENTANCE - No longer kills Keeper when picked up, just reduces coin health to 1, UNLOCK: Unlock this item by beating the Chest with Azazel, * devil pool, devil room pool, devil deal, red devil sign, abandon, abadon, pentagram, Isaac leaves a trail of tar behind him which will slow down enemies that walk over it, Tears have a chance to slow enemies and their projectiles for a short period of time, The chance to slow enemies can improve based on your luck stat and will always slow enemies at +18 Luck, * item room, treasure room, item room pool, black, grey, gray, The Stop Watch applies a permanent but slight slowing effect to all enemies and their projectiles, The slowing effect has a reduced effect against Brimstone lasers fired by enemies, REPENTANCE - Stop Watch now slows down all enemies in the game once again, but the slow effect is much less drastic. Counts as 1 of 3 angel items needed towards the Seraphim transformation. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies), Isaac will now automatically charge up tears, allowing you to store them up and fire them rapidly for a short time, Any time you aren't firing tears, the charge bar will start filling up, for up to 3 seconds. If the player has all mapping effects, it grants the "I can see forever!" Best QoL Mods For The Binding Of Isaac: Repentance - TheGamer (Does not roll your devil deal items), 5 Dot - Reroll and restart the current floor (Forget Me Now effect), 6 Dot - Reroll all of your items and all the pickups on the entire floor (Combined 1 + 3 + 4 rooms), The same order as the in-game collection page. See the dedicated Devil room page for more details, Reveals the entire map and shows the icons for every room which has one, This is completely useless if you currently have both the Treasure Map and The Compass, Doubles your current red hearts up to full health, * , the lost item pool, playing, card, white, red, When used, turns all pickups, chests and non-boss enemies in the room into Bombs, UNLOCK: Unlock this item by getting a 3 win streak, When used, turns all pickups, chests and non-boss enemies in the room into Coins, UNLOCK: Unlock this item by defeating The Lamb in under 20 minutes, When used, turns all pickups, chests and non-boss enemies in the room into Keys, UNLOCK: Unlock this item by defeating The Lamb without taking hearts, coins and bombs, When used, turns all pickups, chests and non-boss enemies in the room into Hearts, UNLOCK: Unlock this item by defeating any floor after Basement I with only half a heart of health (works as The Lost), Teleports you to the Devil Deal Room on the current floor, When used, instantly kills you and spawns 10 pickup on the floor, Each of the 10 things spawned can be any type of consumable or sometimes a pedestal item (up to a maximum of 3 pedestal items), Any pedestal item created by Suicide King will be related to the room where it was used, meaning that using it in the Angel room will spawn Angel room items, UNLOCK: Unlock this card by beating Challenge #7 (Suicide King), UNLOCK: Unlock this card by defeating Mega Satan as Tainted Magdalene, A card which can be thrown as a projectile directly infront of Isaac, instantly killing anything it hits, including most bosses, If thrown at a multi-phase boss with multiple forms such Satan, Mega Satan or Hush it will only kill that particular phase of the boss, If thrown at a multi-phase boss that works from a single health bar such as Isaac, ??? Spindown Dice is the only dice item that cannot be copied by the D Infinity. Stat Down pills do nothing, and items like Experimental Treatment increase stats but don't reduce any, This effect works on items that apply negative stat modifiers, such as Soy Milk, This effect works for anything that gives temporary buffs, like Devil/Strength cards, or kill bonuses like Bloody Lust, If you somehow lose Rock Bottom, your stats will go back to normal, UNLOCK: Unlock this item by defeating the Boss Rush as Jacob & Esau, Bombs now explode with a random effect (e.g.